🧩 Mental Health

Autism Spectrum Disorder

A lifelong neurodevelopmental difference affecting social communication, sensory processing and behaviour.

Overview

Autism affects ~1 in 100 people. It is not an illness but a different way the brain processes information. Strengths often include attention to detail, deep focus and pattern recognition. Co-occurring conditions (ADHD, anxiety, learning difficulty, epilepsy) are common and shape support needs.

Symptoms

  • Differences in social communication: eye contact, reciprocity, conversation flow
  • Restricted, repetitive behaviours or intense interests
  • Sensory sensitivities (sound, light, texture, taste)
  • Need for routine; distress at unexpected change
  • Delayed or atypical language development

Risk factors

  • Family history of autism or related conditions
  • Genetic syndromes (Fragile X, Rett, tuberous sclerosis)
  • Premature birth, low birth weight

Causes

  • Strongly genetic (heritability ~80%); polygenic and rare variants
  • Advanced parental age (small contribution)
  • Prenatal factors: valproate exposure, maternal infection

🚨 Red flags — seek urgent care

  • Loss of previously acquired language or skills (regression)
  • No babbling by 12 months, no words by 16 months, no 2-word phrases by 24 months
  • Self-injurious behaviour
  • Severe meltdowns with safety risk

When to seek care

  • Parental concern about communication, social or sensory development
  • Health visitor or school raising developmental concerns
  • Sudden behavioural change in a diagnosed person — exclude pain, illness, environment change

Diagnosis

  • Multidisciplinary assessment (paediatrician, psychologist, speech therapist)
  • Standardised tools: ADOS-2, ADI-R, 3Di
  • Developmental history, school observation, sensory profile
  • Screen for co-occurring conditions: ADHD, anxiety, learning difficulty, epilepsy, sleep disorder
  • Genetic testing (array CGH, Fragile X) and hearing/vision assessment

Treatment

  • Personalised support plan — neurodiversity-affirming
  • Early intervention (speech and language, occupational therapy, parent-mediated programmes)
  • Education support: EHCP, sensory adjustments, predictable routines
  • Treat co-occurring conditions: methylphenidate/atomoxetine for ADHD, SSRIs for anxiety, melatonin for sleep
  • Behavioural and mental-health support; avoid coercive 'normalisation' approaches

Prevention

  • No prevention; focus is timely identification and support
  • Avoid sodium valproate in pregnancy

Complications

  • Mental health: anxiety, depression, suicidality (higher rates)
  • Burnout, school refusal
  • Self-injurious behaviour in some
  • Diagnostic overshadowing — physical illness missed

Prognosis

Autism is lifelong. With understanding, accommodations and treatment of co-occurring conditions, autistic people lead full and meaningful lives.

Education & self-care

Autistic people thrive with environments that accommodate sensory and communication differences. Early identification opens doors to support — at any age.

Frequently asked questions

Do vaccines cause autism?

No — this has been repeatedly and definitively disproved.

Can adults be diagnosed?

Yes — many autistic adults are diagnosed later in life, especially women and people from minoritised groups.

Is there a cure?

Autism is not a disease to cure. Support focuses on strengths, accommodations and co-occurring conditions.

Medically reviewed by Dr. Handel Emery, MD, FRCP (UK) · Last reviewed 2026-06-08